HEXIMAR OINTMENT (CALCIPOTRIOL ANHYDROUS IP 50 mcg) | 15g/0.53oz

Indications:

Heximar® calcipotriol – is an analogue of the natural active metabolite of vitamin D3 with a wide range of pharmacological activity in the form of ointment for the topical treatment of psoriasis.

It inhibits proliferation of keratinocytes, promotes the differentiation of the epidermis and has a significant effect on cytokines and T-cells in the skin.

Properties:

• for the treatment of psoriasis vulgaris and psoriasis nail in adults;
• affects on all links in the pathogenesis of psoriasis;
• can be combined with other methods for the treatment of psoriasis

Release form:

ointment for external use 15g/0.53oz

Composition:

each gramm contains:

calcipotriol anhydrous IP – 50 mcg in a ointment base base q.s.

Contraindications:

• hypersensitivity to calcipotriol and any auxiliary component of the preparation;
• pregnancy and lactation;
• children up to age 18;
• diseases associated with impaired a calcium metabolism;
• psoriasis of the scalp in the acute stage;
• spotted, erythrodermic, exfoliative and pustular psoriasis;
• renal insufficiency or acute liver failure;
• viral lesions of the skin, fungal or bacterial skin infections, parasitic infections;
• cutaneous manifestations of tuberculosis or syphilis;
• rosacea, perioral dermatitis, acne vulgaris, ulcers, sores and genital itching;
• skin atrophy;
• the fragility of the skin vessels.

Carefully:

• hypercalcemia;
• hypercalciuria;
• hypervitaminosis D;
• nephrolithiasis;
• age over 65 years.

Side effects of the preparation

The most typical: local skin irritation.

Typical: erythema, and itching of the skin.

Atypical: dermatitis (including dermatitis and perioral facial skin in the application of the solution); exacerbation of psoriasis.

Very rare: hyperpigmentation, hypercalciuria, hypercalcemia.

There are reports on the development of photosensitivity and hypersensitivity reactions.

Precautionary measures:

• avoid contact with the face and mucous membranes of the mouth;
• patients should limit or avoid excessive exposure to natural and artificial sunlight;
• use of the drug in doses higher than recommended may cause an increase in the concentration of calcium in the blood (hypercalcemia). When canceling the drug, concentration of calcium in the blood rapidly normalized;
• can be combined with PUVA-therapy;
• can not be used together with the topical preparations containing salicylic acid.

Dosage and how to use:

• before use, consult your physician;
• apply a small amount directly to the damaged area 1-2 times a day (maximum daily dose – should not exceed 15 grams, week – no more than 100 grams);
• treated area should not be more than 30 % of body surface;
• after wash your hands;
• the recommended period of treatment – 4 weeks;
• second course should be agreed with your doctor.

Shelf life:

24 months

Storage conditions:

• stored at temperatures up to 30 ° C;
• store in a dry and dark place;
• keep the tube away from children;
• do not freeze.