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Brand: Galderma
Product Code:160
Availability: In Stock
Country of manufacture: USA
2 or more $117.80 3 or more $116.45 4 or more $115.60 5 or more $114.50

Melasma is a common skin disease that causes brown or tan spots on the skin due to the body producing too much melanin, a natural substance that gives color to skin, hair, and eyes.

One of the most complex diseases of hyperpigmentation is melasma. It is emotionally and psychologically destructive for people and has a negative impact on their quality of life.

There are many factors associated with melasma, including the use of birth control pills, hormone replacement therapy, cosmetics, and anticonvulsants. Hyperpigmentation usually appears on the face, although it can also develop on the forearms and neck.

Exposure to the sun is also a major cause of melasma because ultraviolet (UV) sunlight increases melanin production.

People of Latin, Asian, Indian, Middle Eastern, Mediterranean and North African descent, as well as people with a family history of melasma, most often suffer from this disease.

Tri-Luma® cream is indicated for short-term (up to 8 weeks) treatment of moderate to severe melasma of the face with measures to prevent exposure to the sun, including the use of sunscreens.

Galderma Laboratories, LP Tri-Luma Cream, the only triple combination topical FDA approved drug.

It contains a clinically proven formula that combines the three active ingredients: fluocinolone acetonide 0.01%, a mild corticosteroid that reduces inflammation; hydroquinone 4%, a depigmenting agent that interrupts the formation and synthesis of melanin to help lighten the skin; and tretinoin 0.05%, which helps increase the rate of renewal of skin cells to exfoliate the skin.

Release form:

cream – 15g/0.53oz

Composition: active: hydroquinone 40 mg, tretinoin 0.5 mg, fluocinolone acetonide 0.1 mg; additional: butylated hydroxytoluene, cetyl alcohol, citric acid, glycerin, glyceryl stearate, magnesium aluminum silicate, methyl gluceth-10, methylparaben, PEG-100 stearate, propylparaben, purified water, sodium metabisulfite, stearic acid, and stearyl alcohol.


  • allergy to any of the components of the cream;
  • pregnancy and lactation;
  • inflammatory / eczematous skin diseases (rosacea, seborrhea, psoriasis, dermatitis) wounds and burns;
  • photosensitivity of the skin;
  • rectal disease and Addison's disease;

Side effects:

Often: dryness, peeling, redness, itching and burning.

Very rarely: severe irritation, painful burning, darkening of the skin, blistering, crusting.

Warning! Stop use and consult your doctor if you have any of these signs of an allergic reaction: urticaria, shortness of breath, swelling of the face, lips, tongue, or throat.

How to use:

  • apply 1 time in the evening a small amount on clean and previously dry skin, pointwise on problem areas;
  • after washing your hands;
  • don’t apply other products within 1 hour after applying Tri Luma cream;
  • after an hour, if you feel dry, use a moisturizer;
  • therapy time – as recommended by your doctor;


  • don't use substances that may irritate or dry the skin during therapy;
  • be sure to use sunscreen + SPF15 or more during the day;
  • keep away from sensitive areas of the face. In case of accidental contact with eyes, rinse thoroughly with warm water.

Storage conditions:

  • at temperatures, up to 25 ° C in a dark place and out of reach of children;
  • after opening, store at 2-8 ° C and not more than 6 months.
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